Protocol 02 · Perimenopause

Perimenopause & Healthspan Protocol

Navigate the menopausal transition with precision — measuring what matters at the cellular level.

"I can feel my body changing. I want to get ahead of it before things get worse."

Does this sound like you?

What keeps her up at night.

You are in your 40s or early 50s. Your body is signalling change: fatigue that coffee cannot fix, sleep that does not refresh, hair thinning, and a temperament you barely recognise. Your doctor watches the three highs — but nobody is looking at why your body is aging faster than it should.

  • Increasing fatigue, brain fog, and disrupted sleep patterns
  • Hair loss, skin changes, and body composition shifts
  • Worsening stress response amplifying perimenopause symptoms
  • The three-highs: cholesterol, blood pressure, blood sugar creeping upward
  • Bone density and fracture risk as oestrogen declines
  • Whether current supplements are actually doing anything
The Science

8 of 12 Hallmarks of Aging.

Perimenopause is not just a hormonal event — it is a systemic acceleration. Oestrogen decline triggers mitochondrial dysfunction, cellular senescence, epigenetic drift, and chronic inflammation. Your protocol covers the broadest hallmark range of any Vivere bundle.

H1
Genomic Instability
H2
Telomere Attrition
H3
Epigenetic Alterations
H4
Loss of Proteostasis
H5
Disabled Macroautophagy
H6
Nutrient Sensing
H7
Mitochondrial Dysfunction
H8
Cellular Senescence
H9
Stem Cell Exhaustion
H10
Intercellular Comms
H11
Chronic Inflammation
H12
Dysbiosis
Menopause Shield Bundle

Six precision diagnostics.

A 360-degree view of your cellular aging — from epigenetic age to mitochondrial energy to skeletal integrity.

1
Epigenetic Age Clock
DNA methylation biological age vs. chronological age
H2 H3
$450
2
Intracellular NAD+ Assessment
Actual NAD+ inside cells — energy and DNA repair capacity
H7
$600
3
Cellular Senescence Dual-Panel
IL-6 + C1q — zombie cell burden and neuro-immune status
H8 H10
$649
4
Structural Longevity Scan
Bone density, muscle mass, visceral fat, fracture risk (DEXA + FRAX)
H9
$199
5
Metabolic Resilience Score (NMR)
NMR metabolomics — three-highs risk and metabolic resilience
H6 H11
$399
6
Clinical Micronutrient Audit
Iron, Zinc, Selenium, Vit D, B12 — hormonal cofactors
H10
$499
Bundle total$2,796
Every bundle includes

More than tests.

  • Initial 45-minute deep-dive consultation with a longevity physician
  • Personalised Vivere Master Blueprint with supplement and exercise prescription
  • Digital results dashboard with longitudinal tracking
  • Two follow-up tele-reviews (8 weeks and 16 weeks)
  • Optional add-on: Metabolic Recomposition Protocol with GLP-1 therapy if indicated
Your Journey With Vivere

Baseline. Decode. Prescribe. Track.

Step 1
Baseline

Comprehensive blood draw, body composition scan, and health history review. We establish where you stand across all measured hallmarks.

Step 2
Decode

Your physician maps every result to the Hallmarks of Aging, showing exactly which biological clocks are running fast — and which you can slow.

Step 3
Prescribe

A bespoke protocol: targeted supplementation (NAD+ precursors, omega-3, vitamin D), exercise calibrated to your VO2max, and nutrition adjustments.

Step 4
Track

Quarterly re-testing of key markers to measure biological age reversal. Your dashboard shows progress over time, not just snapshots.

Frequently asked

Your questions, answered.

Is this protocol an HRT replacement?

No. This protocol measures the cellular aging signals that intensify around perimenopause. It is fully complementary to hormone replacement therapy and often makes HRT decisions more informed — your physician can see exactly which hallmarks are accelerating and tailor the conversation.

What's actually in the GLP-1 add-on?

If your visceral adiposity, metabolic age, or three-highs risk indicates clear benefit, your physician may prescribe GLP-1 therapy under monitoring. It is not included in the base bundle price and is only prescribed after clinical assessment.

How is biological age "reversed"?

Biological age — measured by the epigenetic clock — responds to targeted intervention. Sleep, exercise (especially resistance training), nutrient sufficiency, and selective supplementation all move the needle. We re-test at 8 and 16 weeks to confirm trajectory.

I'm post-menopausal. Is this still relevant?

Yes. The Menopause Shield Bundle is calibrated for the transition AND the years after. Bone density, mitochondrial function, and cellular senescence continue to be the dominant aging signals well past menopause.

Can I add a thyroid panel?

Absolutely. Hashimoto's and subclinical hypothyroidism are common in this life stage. We add full thyroid panels (TSH, fT3, fT4, TPO antibodies) at clinical discretion.

Perimenopause is not a decline. It is a turning point.

The question is whether you navigate it with data or with guesswork.

Book your discovery session →

Vivere Longevity protocols are physician-supervised and personalised. GLP-1 therapy is prescribed only after clinical assessment and is not included in the base bundle price. All prices are before GST. Vivere Longevity operates from Paragon Medical Centre, 290 Orchard Road #17-11, Singapore 238859.