Vivere Longevity — Women’s Precision Protocol

Perimenopause &
Healthspan

The window before menopause is your highest-leverage opportunity to prevent the cardiovascular, bone, and cognitive decline that follows — if you act while the biology is still working for you.

The Perimenopause Window

The years before the Final Menstrual Period are when intervention matters most.

Perimenopause is not a waiting room for menopause. It is the period of active hormonal transition during which cardiovascular risk accelerates, bone density begins its steepest decline, and cognitive changes emerge — often years before most women recognise them as hormonally driven. Standard health screens are not designed to detect this transition.

The Vivere Perimenopause Protocol establishes your complete biological baseline at the moment when intervention is most effective — mapping the hormonal, cardiovascular, skeletal, and cognitive changes already underway, and building a programme around the highest-leverage actions available now.

Hormonal Transition Cardiovascular Prevention Bone Density Cognitive Baseline Biological Age Healthspan Optimisation
Molecular Basis

Hallmarks of Aging Accelerated During Perimenopause

Perimenopausal hormonal fluctuation affects multiple aging pathways simultaneously — epigenetic drift, metabolic resilience, cellular senescence, and intercellular signalling are all in active transition.

H1
Genomic Instability
H2
Telomere Attrition
H3
Epigenetic Alterations
H4
Loss of Proteostasis
H5
Disabled Macroautophagy
H6
Mitochondrial Dysfunction
H7
Cellular Senescence
H8
Stem Cell Exhaustion
H9
Altered Intercellular Communication
H10
Chronic Inflammation
H11
Dysbiosis
H12
Deregulated Nutrient Sensing

López-Otín et al., Cell 2023. Highlighted hallmarks reflect primary mechanistic targets of this protocol.

Precision Investigations

Your Perimenopause Biomarker Panel

Seven investigation sets establishing your complete biological baseline during the transition window — each selected because it enables a high-impact, modifiable intervention.

Your Vivere Journey

From Baseline Assessment to Personalised Programme

A structured six-step programme establishing your complete perimenopausal baseline and delivering an evidence-ranked intervention plan while the window for greatest impact is still open.

The Perimenopause Window

The 4–8 years before the Final Menstrual Period are the highest-leverage window for preventing post-menopausal cardiovascular, bone, and cognitive decline.

Timing

Oestrogen begins declining up to 10 years before the last period. The cardiovascular and bone protection it provides is already diminishing.

Intervention Window

Lifestyle and hormonal interventions started during perimenopause are significantly more effective than those started after menopause.

1

Longevity Consultation

Physician-led review of your symptom timeline, hormonal history, and cardiometabolic risk.

2

Cardiovascular & Hormonal Bloods

Fasting panel covering hormonal transition markers, cardiovascular risk, and bone health.

3

DEXA Body Composition

Bone density, muscle mass, and body composition measured and scored against Asian-specific references.

4

Epigenetic Age Clock

DNA methylation assessment measuring your biological age and pace of aging during transition.

5

Cognitive Baseline

Standardised cognitive assessment establishing your pre-transition performance baseline.

6

Protocol Review & Programme

Your physician presents a personalised plan covering hormone therapy options, training, nutrition, and monitoring.

Every result is reviewed in a physician-led consultation. Your protocol is built on your data, not a template.

Book a Consultation

Begin Your Perimenopause
Longevity Assessment

Vivere Longevity · 290 Orchard Road, #17-11 Paragon Medical, Singapore · By appointment

Book a Consultation